Captopril Overview

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Captopril is a medicine that fits into a category called ACE inhibitors. ACE inhibitors are a group of drugs used to treat high blood pressure in adults. They can be used alone or with other medications.

If you are pregnant, you should not take Captopril or other ACE inhibitors. Side effects include death of an unborn baby or serious birth defects. Kidney problems are also a risk of taking this drug and this group of drugs. The kidney problems could be new or a worsening of already existing kidney problems. Symptoms of this include sudden weight gain and swelling of the arms, legs, and feet. The most common side effects of taking ACE inhibitors are dizziness, dry cough, and sore throat. 

In June of 2006, the Food and Drug Administration released a warning stating that taking ACE inhibitors in the first three months of pregnancy (first trimester) increases the chances of birth defects. The issued this warning following an experiment whose results were published in the New England Journal of Medicine in the same month.The study showed a slight increase in the chances of birth defects in babies whose mothers had taken ACE inhibitors; however, the increase was small and the study has not been repeated. Prior to this study, it was already known that taking ACE inhibitors during the second and third trimesters could hurt the baby.


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