At the Mayo Clinic and Harvard Medical School, researchers have found that a protein used to fight cancer may actually help it spread. The researchers studied FOXO3a which works to regulate gene expression. For years, researchers have held the belief that activating the transcription factor would help fight cancer.
According to the new research, however, FOXO3a becomes active when cancer cells are deprived of nutrients, causing the protein to enable the cells to invade healthy tissue. The results of the study were published in the September 3 issue of Molecular and Cellular Biology.
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